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Description
Elegant structural characterization of the well-known ANT enables structure-guided investigations on the SLC25 transporters of unknown functions

These alterations cause elevated intracellular levels of Na and Ca, disrupt ionic homeostasis, and result in cell swelling [103]

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Gauge needles were inserted into the trachea of each mouse to slowly inject 1 mL PBS into the lungs before withdrawn 2 times
Furthermore, studies using DSSinduced colitis models demonstrated significantly increased syn expression in the colon and notable syn deposits in the brain [132], supporting the hypothesis that the gastrointestinal tract serves as an initial site for syn pathology, which may then propagate to the CNS via the vagus nerve [23]
