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doi: 10.1006/hbeh.1998.1507 22 CamachoF

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Nelson: Usually, acral lentiginous melanoma can appear as an unevenly pigmented black or brown spot on the palm or sole that looks different from the rest of the patients skin and grows over time

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In clinical trial, over half of the patients enrolled had hepatic metastasis and 63.6% of treated patients achieved stable disease (NCT05415072)

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In small phase I clinical studies, intravenously administered ascorbate was safe

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