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Baseline levels of these markers are low in healthy individuals, whereas increased circulating LPS/endotoxin levels are related to an impaired mucosal barrier and increased levels of D-lactate are correlated with intestinal injury [38]

(1995) has been extensively used (Gomez-Alonso et al

Speakman, E

Chang et al [57] focused on enteric glial CRF-R1/Cx43 to alleviate stress-induced colonic motility and found that modulating this signalling pathway may benefit those with stress-related GI dysfunction
