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PatelAKReddyVAraujoJF.Physiology
Ameliorative Effect of Sinapic Acid on Dextran Sodium Sulfate- (DSS-) Induced Ulcerative Colitis in Kunming (KM) Mice
Two-way ANOVA ( c, d )
NF - B pathway: inhibits NF - B p65 nuclear translocation, reduces I B phosphorylation, blocks osteoclast activation and bone resorption function
Additionally, HDAC6 inhibitors activate redox-regulating proteins like peroxiredoxins (reduce ROS) and support the function of the autophagy and ubiquitin-proteasome system (UPS) (both are impaired in PD patients) 62
Beyond its role as a shield, glutathione is also a vital player in the detoxification process
