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Potential Benefits of Boosting NAD+ Laboratory studies and emerging clinical research suggest that increasing NAD+ levels may offer several potential benefits: Improved Energy Levels: By enhancing mitochondrial function, NAD+ can support more efficient energy production within cells

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It is known that reduction in CD38 expression on BM and circulating MM cells occurs rapidly after daratumumab initiation with significantly lower expression levels after the first infusion compared with baseline (potentially due to elimination of MM cells with high CD38 levels, endocytosis, or release in microvesicles), that may persist for at least 6 months after discontinuation [35]