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Heusch G, Libby P, Gersh B, Yellon D, Bohm M, Lopaschuk G, Opie L

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[7] [25] Prostaglandin E2 (PGE2) is an essential activator of the canonical Wnt signaling pathway

Rahmattulla et al

In an autocrine mechanism, SASP factors reinforce the cellular senescence of the senescent cells themselves, while in a paracrine mechanism, they are responsible for inducing senescence in surrounding cells [35]

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