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Certain groups are at higher risk, including older adults, vegans, individuals with pernicious anaemia, those with malabsorption conditions such as Crohn's disease or coeliac disease, and people taking certain medications (metformin, proton pump inhibitors)

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Archived from the original on 27 September 2007

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Treatment reduces circulating markers of metabolic dysfunction and inflammation, creating a more favorable metabolic environment that supports insulin sensitivity and glucose regulation