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This amino acid can serve as a respiratory substrate that enters the TCA cycle in mitochondria, thereby driving ATP production (Obrist et al., 2018)

Moreover, these multi-protein complexes are continuously exposed to a GSH-depleted environment in Gclc -deficient FoB, which might alter protein folding or their targeting to the mitochondria

Additionally, Pink1 may be involved in the regulation of mitochondrial fission and fusion homeostasis independently of mitophagy

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But three things limit what these animal studies can tell us

Pregnancy and breastfeeding represent absolute contraindications based on precautionary principles