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It could be, for example, an adapting nerve system

Epigenetic modifications, such as DNA methylation and histone acetylation, also play a role in regulating gene expression in response to mechanical stress and training

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A study found that by examining the postmortem brain tissue of suicidal patients with depression, the astrocyte-specific methylation map in the genome showed that glutamate receptor ionotropic kainate 2 and brain-rich guanosine kinase-related protein, which are associated with depressive psychopathology, were less methylated 134

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