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The study comprised a single intravenous (i.v.) administration of the peptide (20 g/kg in Sprague-Dawley rats and 6 g/kg in beagle dogs), a single intramuscular (i.m.) administration of 20, 100, or 500 g/kg (rats) and 6, 30, or 150 g/kg (dogs), and repeated i.m

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Integrated Approach to Wound Pain Management: Pharmacotherapy and Wound Dressings The management of wound-related pain primarily relies on systemic administration of analgesics such as paracetamol, NSAIDs, opioid analgesics, gabapentinoids (gabapentin, pregabalin), and tricyclic antidepressants (TCAs)

Activation of the 3-adrenergic receptor results in the formation of a ligand-induced complex between perilipin, caveolin-1, and the catalytic subunit of PKA in adipocytes (23)