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administration of glucose, suggesting a link between LAC-related transport of acetyl groups and glucose signaling pathways, especially under conditions of metabolic stress [69]

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Systematic literature review and evidence grading The methodology used for collecting the evidence base for this guideline is essentially that used by the Scottish Intercollegiate Guideline Network (SIGN, A systematic literature review on MMA/PA from the time of description of each disease until December 2011 was carried out using mainly Medline, Embase, the Cochrane Library, MedLink, and Orphanet

(2018) 50:e13012

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Moreover, it is possible to estimate that dogs and cats with cachexia or sarcopenia have an increase of at least 40% in protein intake to avoid loss of muscle mass and lean body mass