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In summary, some controversies remain regarding the effects of SSRIs on embryonic development, and heterogeneity may exist owing to the different definitions of congenital malformations used in different studies, especially those related to CHD (Figure 2)

Mechanical processing in the stomach liberates these compounds, facilitating absorption in the small intestine, while unabsorbed fractions reach the large intestine for microbial metabolism, generating bioactive metabolites that subsequently enter systemic circulation

with several inducers of gst-4 including H 2 O 2 and sodium azide being shown to be skn-1 dependent [118]

Transl Stroke Res (2021) 12(4):61530

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