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Description
ROS must pass through the mitochondrial membrane to enter the cytoplasm, and the destruction of mitochondrial membrane integrity and loss of membrane potential lead to the release of ROS into the cytoplasm [54]

N.AlamsjahM

Despite these insights, most clinical trials fail to stratify outcomes by sex, obscuring gender-specific mechanisms

This is an inefficient process that does not always result in higher cellular levels
An appropriate management scheme is clearly needed for infants with HT-1 identified by NBS or following presentation with clinical symptoms

31 Liu et al
