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These mechanisms are scientifically interesting, but clinical translation requires careful study

The cDNA was stored at -80C prior to use in RT-PCR

Various classes of antibiotics such as macrolides, aminoglycosides, and amphenicols inhibit bacterial protein synthesis, they also block polypeptide synthesis in the mitochondria (85, 86)

V.PonS.et al (2005a)

Collectively, the findings suggest that ATF4 is not the sole transcriptional mediator of MR and that the diet is producing additional regulatory input to genes of the ISR 27

While the dysbiosis-mediated induction of LGS initiates an inflammatory response, some microbial products reinforce TJ integrity