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Together with the fact that the intestinal lumen diameter is much greater in humans than in mice, this observation suggests that pharmacological claudin-2 channel inhibition is unlikely to cause intestinal obstruction in humans

Oral BPC-157 capsules exist and have some utility for gut-specific indications because of localized activity in the GI tract

References [i] Gwyer, D., Wragg, N
[PubMed: 4721404] 61
