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Despite the early termination of the trial, it is interesting to note that 13 of 140 patients had a median duration of response of 10.2 months, indicating that these patients benefited from combination therapy and that exploring the mechanisms of this benefit should be the focus of future research
Reprogramming of lipid metabolism is one of the important features of malignant tumors, including fatty acid synthesis in addition to FAO
doi: 10.1046/j.1468-3083.2000.00143.x
Paraoxonases (PONs) were originally named for their ability to hydrolyze the neurotoxin paraoxon and this activity is still routinely used to assay paraoxonase activity in plasma
As we've explained above, doses in excess of 1 mg per day are rare in past studies
European Journal of Applied Physiology 1990;60:1-6.
