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Results 8 studies that reported measurements for 230 patients with depression and 216 controls were included

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This action leads to improved insulin sensitivity: in skeletal muscle, MOTS-c treatment boosts insulin-responsive glucose uptake and utilization, effectively enhancing insulin sensitivity and glucose balance in the body

their highly hydrophilic nature and low capability to permeate through biological barriers (cell membranes) are additional factors that limit their applicability

During metabolism most drugs lose the pharmacological activity and are excreted from the body