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GLN catabolism inhibits intracellular GSH depletion and subsequent ROS generation [49, 95], as well as affecting the TCA cycle [96]

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R., Reilly, K

Thioredoxin reductases (TXNRDs) employ NADPH as an electron donor to revert oxidized TXN to a reduced dithiol, the oxidation status of which is critically implicated in regulating various cell behaviors including proliferation and apoptosis 51

Hugdahl, K