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Our group, working with partially deficient IGF-1 mice, has demonstrated that the liver is capable of expressing IGF-1R (which under physiological conditions it does not [99]) as a defence mechanism (peer review)

Similar reductions in GSH have been observed in ME/CFS patients, further supporting the link between oxidative stress and chronic fatigue conditions (Jason et al., 2022

[DOI] [PMC free article] [PubMed] [Google Scholar] 92.Choi JB, Lee SG, Kim MJ, Kim TH, Ban EJ, et al

This single substitution shifts biological activity from broad tissue repair (GHK-Cu) toward targeted hair follicle stimulation (AHK-Cu)

doi: 10.1128/JVI.00603-16

Despite structural differences, Granatin A and Granatin B generally exhibit similar bioactivities, primarily in anti-inflammatory and anticancer applications
