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The most effective cerebral protection protocol integrates three components: (1) preoperative cerebrovascular reserve assessment, (2) intraoperative NIRS monitoring with protocolized interventions, and (3) maintenance of cerebral perfusion pressure through goal-directed fluid and vasopressor management (74)

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Goldman, B

[DOI] [PubMed] [Google Scholar] 100.Dulcich M.S., Hartman R.E

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When the tumor size was about 60 mm 3 , DMSO or the CHK2 inhibitor (1 mg/kg) was administered intraperitoneally on alternate days for 20 days after randomly grouped ( n = 5/group)