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A separate 2025 narrative review by McGuire and colleagues asked a blunter question in its title: "Regeneration or Risk?" [2] Their conclusion: the preclinical evidence is consistently positive, but the absence of human data makes it impossible to generate evidence-based practice guidelines

underwhelming evidence against

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Methylene Blue [hsdb] 142

Remarkably, PD is not the only disease associated with -Syn amyloid formation

Both angiogenesis and vasculogenesis have been shown to play roles in progression of diseases including cancer, ischemia, and arterial stiffening (63, 64)