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Relevant to this, the efficacy of inhibitors directed against several lipogenic enzymes (including fatty acid synthase) was reviewed in refs

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Here, we summarize the features, process, function, and mechanisms of ferroptosis, discuss its relevance with oxidative stress and cellular inflammation linking to cardiovascular disorders, raise the unsolved mysteries of ferroptosis, and provide new insights to consider the ferroptosis as the therapeutic target for the prevention and treatment of CVDs

Kinnaird, A., Zhao, S., Wellen, K

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