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Homocysteine is a sulfur-containing amino acid synthesized as an intermediate product of methionine metabolism (an essential amino acid), with incredible and vital functions for the body (production of cysteine, taurine, carnitine, precursor of Same- methyl group donor, etc.), that is, it helps us to have our physical and mental health in the best possible state

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VHL alterations in RCC cells lead to the activation of hypoxia-inducible factors and their downstream target vascular endothelial growth factor, and to the reprogramming of multiple cell death pathways and metabolic weakness, including ferroptosis, which are associated with targeted therapy or immunotherapy