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Recent studies have shown that the ability of cells to generate mitochondrial supercopmplexes enhances exercise endurance and, at least in mice, results in suppression of cellular senescence, a key characteristic of aging cells
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Heat production from uncoupling electron transport would be another- this is thought to lead to death before ATP depletion
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GPX3 mRNA is expressed in the kidney, pancreas, lung, breast, brain and gastrointestinal tract, but the majority of GPX3 is expressed in the plasma which is kidney-derived
