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The Pentose Phosphate Pathway (PPP) is one of the most significant metabolic pathways for NADPH generation

In addition to H 2 O 2 and small molecule hydroperoxides, it is also capable of reducing complex lipid compounds such as phospholipids, cholesterol and cholesterol lipid hydroperoxides

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Jul 2011;6(7):820-7

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Abbreviations BBB: Bloodbrain barrier BrdU: Bromodeoxyuridine CNS: Central Nervous System DG: Dentate gyrus GCL: Granular cell layer GDF11: Growth Differentiation Factor 11 IP: Intraperitoneal NSC: Neural stem cell OPC: Oligodendrocyte precursor cell rGDF11: Recombinant GDF11 SGZ: Subgranular zone SVZ: Subventricular zone TAM: Tamoxifen TGF-: Transforming growth factor-beta References McPherron AC, Lawler AM, Lee S-J