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Further confirmation is required for the role of genotype and central and GI effects of GLP-1RA 112
PD also comprises a group of non-motor symptom complexes that may appear years before the motor symptoms [13]

A Phase 2 trial (NCT01311518) was designed to test RGN-352 in ~75 heart attack patients, but was placed on FDA clinical hold in 2011 due to manufacturing (GMP) compliance issues at the contract site not safety concerns with the drug itself

Medvidovic-Grubisic et al., 2017
Several other studies also studied the effect of IN insulin delivered using the nebulizer device ViaNase and observed improvements in cognition, functionality, cortical blood flow, and vasoreactivity [80,81,82,83]

Army Medical Center at Fort Hood in Texas
