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Histopathological hallmarks include focal demyelinated lesions characterized by oligodendrocyte (OL) cell death, axonal damage, gliosis, microglial activation, and infiltration of lymphocytes and macrophages [1,2]

Briefly, cellular pellets (10 g) were mixed with 30 l 5% metaphosphoric acid, and then frozen and thawed twice using liquid nitrogen and 37 C water

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Under iron-catalytic conditions, maintenance of the Fe 2 + /Fe 3 + redox couple promotes extensive peroxidation of PUFA-containing membrane phospholipids and drives ferroptotic execution in cancer cells 190,191

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Aerobic exercises can range from walking, running or bike riding but the key thing here is that these forms of exercise are all steady-sate activities