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For extracellular amyloid quantification, PMEL-knockout MNT-1 cells, transformed with Tet-on-inducible wild-type or G175S PMEL expression plasmids, were cultured in the presence or absence of 0.2 g/ml Dox for 96 h
Collectively, these findings challenge conventional views of MFI2, and our data reinforce its context-dependent tumor-suppressive role, underscoring the need for further mechanistic studies
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