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313 The optimized successor of GKT137831, Setanaxib, overcomes PD-1/PD-L1 resistance by targeting NOX4 in cancer-associated fibroblasts, reversing their immunosuppressive phenotype, and enhancing CD8 + T-cell infiltration

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Dual GSH-exhausting sorafenib loaded manganese-silica nanodrugs for inducing the ferroptosis of hepatocellular carcinoma cells

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On the other hand, SIRT7 can be activated by Linc00886 to reduce H3K18 acetylation on the promoter region of ELF3, thereby inhibiting the expression of ELF3

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Prepdock website ( and AutoDockTools 1.5.7 software were used for adding hydrogens and symmetry related waters, computing Gasteiger charges, and detecting torsion root 59

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2751089, Japanese Pat

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A new field called computational pharmaceutics has emerged in the last ten years as a result of the exponential growth of computing power and algorithms

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