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10.3390/genes10020168 Summary Keywords mitochondrial DNA depletion syndrome, nuclear gene mutation, mtDNA, cardiac disease, ATP Citation Wang H, Han Y, Li S, Chen Y, Chen Y, Wang J, Zhang Y, Zhang Y, Wang J, Xia Y and Yuan J (2022) Mitochondrial DNA Depletion Syndrome and Its Associated Cardiac Disease

Combined, these studies involved fewer than 30 human subjects and lacked control groups none used a randomized, placebo-controlled design

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Xu HJ, Wang LH, Zhang QY, Jiang X, Zhang CR, Zhang YG

The liquid chromatograph was coupled to an Agilent 6475 Triple Quadrupole mass spectrometer operating in ESI mode

The smaller population most likely reflects cells with high autofluorescence, as is often associated with phagosomes in macrophages