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It was recently discovered that NCOA4 engages a [3Fe-4S] cluster 143,144

There is a big difference between hormetic cortisol spikes (exercise, fasting, cold) and chronic cortisol drip (financial stress, bad sleep, anxiety) Hormetic stress: quick spike then shutoff, changes receptor density in a beneficial direction

M., Sparks, J

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Activation of Notch signaling has also been reported to regulate cell proliferation and apoptosis (120)
