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Supplementation of large doses of glycine and serine, precursors of glutathione, can attenuate NAFLD in human and animal models [18, 19]

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Specifically, it produces no IGF-1 elevation (avoiding proliferative concerns), no negative impact on glucose metabolism (avoiding diabetes risk), no fluid retention or edema, and no concerning patterns of joint pain that can occur with growth hormone

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(2021) studied its role in colitis and found that SYD could significantly reduce the inflammatory index and improve the expression of mucins and occludin

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doi: 10.1038/nrmicro3380 24 BorrielloG.WernerE.RoeF.KimA

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doi: 10.3390/ijms25095043 56 KeunenE.PeshevD.VangronsveldJ.Van Den EndeW.CuypersA

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CDDO-methyl ester delays breast cancer development in BRCA1-mutated mice

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