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As yet, whether the ER senses these changes to glutathione directly or indirectlyfor example, through the activity of other codependent pathways such as the thioredoxin pathwayis not clear

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initial diagnosis and prescribed treatment require in-person consultation with the doctor.

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Long-term treatment with ranirestat (AS-3201), a potent aldose reductase inhibitor, suppresses diabetic neuropathy and cataract formation in rats

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