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These metabolites also exhibit potent antiproliferative and pro-apoptotic effects against various tumor cell lines (Lopez et al., 2016

As evident from Figures 2A,B, the colon length of mice with DSS-induced colitis was notably shorter than that of the Control group

The cells were then washed, and the efflux was induced by incubating cells for 1 min in either the absence or presence of non-radiolabeled test compounds at indicated concentrations

GluN2C subunit is critical to normal cortical neuronal oscillations Due to their unique biophysical properties such as reduced voltage-dependency due to a lower sensitivity to Mg 2+ -blockade as well as lack of desensitization 17 , GluN2Ccontaining receptors may be active without the requirement for prior depolarization and via spillover glutamate thereby leading to tonic activity, which can impact neuronal oscillations