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The temperature-sensitive strain pha-4 ( zu225 ) ;smg-1 ( cc546ts ) has been reported to show inactivation of PHA-4 at a restrictive temperature of 20 , due to the mutation ( cc546ts ) background of smg-1 that encodes a component of nonsense-mediated decay (NMD) pathway 38
30 GiangregorioN.TonazziA.ConsoleL.IndiveriC
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It binds MC1R through MC5R non-selectively, which explains both its versatility and its side-effect burden
