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Additionally, since serum GPX-3 concentration was inversely correlated with BVAS, we divided the study participants into two groups according to each of the nine systemic items of BVAS and compared serum GPX-3 concentrations between the two groups (Table 3)

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During this period, cultured chondrocytes gradually lose the proliferative capacity and the potential of generating the cartilage-specific matrix, a phenomenon known as dedifferentiation (Sassi et al., 2014)