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Accessed September 18, 2023

GLP-1-based compounds work primarily through appetite suppression, and the weight loss they produce includes significant lean mass loss (approximately 40% of total weight lost is lean tissue based on STEP trial data)

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Over-dosing means unnecessary side effects, potentially severe ones like nausea, vomiting, or the kind of gastrointestinal issues that make people quit their protocol entirely

Additionally, people with certain digestive disorders, such as Crohns disease or celiac disease, may struggle to absorb B12 from their diet and might require B12 injections to support digestive health