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Additionally, trials of oligonucleotide therapeutics and experiments with some small-molecule NNMT inhibitors in vitro and in preclinical animal models have validated NNMT as a promising therapeutic target to prevent or treat obesity and associated T2D

Tissue Specificity vs Systemic Remodeling Another major distinction is tissue specificity

What works beautifully for one might not be the right fit for another

Disclaimer: All scientific discussion surrounding these compounds must remain within the context of non-human, controlled laboratory research

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