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Vitamin B12 is a water-soluble vitamin that is involved in a wide range of important biological processes

With the aid of Graphpad Prism software version 10.2 (University of Rochester, Rochester, NY, USA), metabolism rates were profiled against the incubation time from which metabolic kinetic parameters were determined

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Mitochondrial glutathione depletion can lead to premature cell death and accelerate the aging process

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Future research should prioritise the enhancement of mucoadhesive properties, the optimisation of permeation enhancers, and the development of novel intranasal delivery devices to maximise clinical efficacy