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Oct 2021;129(4):308-318

In parallel, a growing number of clinical trials targeting aging are underway, providing increasing evidence for the safety and efficacy of these interventions (Wang K

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For example, more ROS are generated by the aged cells than in the young cells and melatonin as the endogenous antioxidant is used to neutralize the overproduced ROS in aging organisms

For a more dynamic prediction of metabolic function, Compass 26 uses a machine learning approach to infer metabolic flux by integrating scRNA-seq data with genome-scale metabolic models