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Increase of Th17 Cell Phenotype in Kidney Transplant Recipients With Chronic Allograft Dysfunction

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Long-term effects unknown

minor swelling and bruising may occur

Measuring binding affinity by R2KD Recent work by Liu and colleagues introduced a novel LO-NMR method that can be used to quantitatively determine the dissociation constant (K D ) of a ligand for a protein from measured R2 values of ligand nuclei at a range of ligand concentrations 40

Researchers planning new work should review the most current literature before designing protocols, with attention to the gap between preclinical breadth and clinical-trial depth