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94 In rats, with the ligation of the inferior caval vein, direct vein injury and thrombosis were counteracted (occlusion up to the right ovarian vein leading to vessel injury, stasis, thrombosis and hemodynamic changes a recapitulation of Virchow)

Patients with underlying liver disease, kidney impairment, or cardiovascular conditions should avoid lipotropic injections without medical supervision

Some patients use DSIP for specific periods of sleep disruption (travel, high-stress periods, training cycles requiring optimal recovery) with targeted short-term protocols, while others implement ongoing protocols with periodic cycling for sustained sleep optimization
