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In hepatocellular carcinoma (HCC), LCACs are effectively loaded into the mitochondria of lymphocytes, resulting in the inhibition of invariant natural killer T (iNKT) cell expansion and the promotion of their senescence while simultaneously facilitating tumor evasion of immune surveillance [66]
Fibroblasts, endothelial cells, vascular smooth muscle cells, and chondrocytes all express the MGP (134)

BA with detergent properties can damage the colonic epithelium when presented in high concentrations in the colon
Similar results were reported in the clinical study of patients with type 2 diabetes, where increased TMAO levels are independently associated with risks of adverse cardiovascular events (138, 139)
[DOI] [PMC free article] [PubMed] [Google Scholar] 60.Willems G
