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In a transgenic mouse model of Parkinson's disease, active immunization with a novel vaccine (AFFITOPE, AFFiRiS) containing short peptides homologous to aSYN conjugated to a carrier caused the formation of antibodies specifically directed against the carboxy terminus of human aSYN, cleared aSYN aggregates, and decreased neuropathology

In contrast, neither Cdkn1a nor Nupr1 expression was significantly altered in OLs at 7 days post-lesion (dpl) or 28 dpl (demyelination and remyelination, respectively) following LPC injection, compared to saline-injected controls (Fig

In cosmetic treatments, glutathione is used for skin lightening by reducing the production of melanin, thereby lightening the skin and reducing hyperpigmentation

Clin Rheumatol 40(4):12211231

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The most striking transformations occur in patients with moderate to severe volume loss, where strategic filler placement creates dramatic improvements in facial harmony and youthful appearance