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This unique characteristic of GSTLs help in the substitution of amino acid in active site residues forming mixed disulfides with thiol group rather than promoting formation of reactive thiolate anion of GSH

[DOI] [PubMed] [Google Scholar] 48.Houseknecht KL et al

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Bowes, S

Cagrilintide is a long-acting peptide engineered to mimic the function of amylin , a hormone normally released alongside insulin by pancreatic beta cells

The process is facilitated by the presence of Polyethylene Glycol, a molecular crowding agent which brings -synuclein molecules in close proximity by displacing water from the immediate vicinity for enhanced hydrogen bonding, non-covalent interactions and hydrophobic interactions (De Luca et al., 2025)