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Biochem J 324 (Part 1): 2528

In APP/PS1 transgenic mice, hippocampal iron levels begin to rise at 6 months of age, with an increase of up to 48% observed by month 8

A., Petros, C., Taylor, E

Dephosphorylation of Tyr-527 by various phosphatases opens the structure and activates the kinase (796, 1087, 1274)

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Iron plays a key role in the differentiation of dendritic cells by supporting the induction of the cyclin-dependent kinase inhibitor p21 ( In a healthy body, immune cells conduct immune surveillance, detecting and eliminating potentially transformed cells before they develop into malignant tumors