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Targeted 1 H-NMR metabolomics was conducted on serum, the liver, the kidney, and the gastrocnemius muscle, as well as the cortex and the hippocampal brain regions in 16-month-old female mice after a 2-month KD

Metformin inhibits the senescence-associated secretory phenotype by interfering with ikk/nf-Kb activation

Broad NF-kB inhibition is relevant across multiple organ systems

The proposed mechanism of meningococcal evasion from the internalization vacuole is illustrated in Figure 1

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