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10.1111/j.1740-8709.2012.00418.x [DOI] [PMC free article] [PubMed] [Google Scholar] 39

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Efficacy is unaffected once the peptide reaches the bloodstream it sits in the bodys own roughly 150 mM saline regardless of what you mixed it with. NAD+ is different: its pain is acidity, not mast cells reconstituted NAD+ sits near pH 3.5