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Just like retinol, the acidity destabilizes peptide bonds

The research basethough extensive, comprising over 100 published studiesis entirely preclinical (animal models and in vitro experiments)

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This decline has led some researchers to speculate that reduced GHK signaling could contribute to age-related impairments in: wound healing tissue repair collagen production While this hypothesis remains under investigation, it helps explain why GHK-Cu supplementationparticularly through topical formulationshas become a focus of dermatologic research