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347 This was achieved by decreasing the expression of proinflammatory cytokines such as tumor necrosis factor (TNF), interleukin-6 (IL-6), and interleukin-8 (IL-8)

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used a repository of transcriptional responses to compounds, the Connectivity Map (cMap) [60], and MANTRA software ( to explore networks of compounds producing similar transcriptional responses

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Nitric oxide induced by BPC 157 contributed to the promoted cell migration The in vitro angiogenic effect of BPC 157 has been shown to promote the cell migration of vascular endothelial cells in our previous study